G6PD supports oxidative PPP NADPH generation
CATALYZESG6PD to nadph; qualitative coefficient 0.72
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Glutathione / NADPH
G6PD NADPH-Generation Terrain
Oxidative PPP support, NADPH generation, and clinical-safety boundaries.
Evidence quality visible
No dosing or treatment advice
Terrain context linked
What The Enzyme Does
G6PD is represented as an oxidative pentose phosphate pathway enzyme supporting NADPH generation in the seed graph.
- Gene
- Glucose-6-phosphate dehydrogenase
- External IDs
- HGNC:HGNC:4057, NCBI_GENE:2539
What The Variants Change
G6PD has a gene and pathway-edge record in Phase 1A, but curated variant controls are not exposed yet.
No curated variant control is exposed for G6PD in Phase 1A.
Downstream Consequences
- The seed graph models G6PD as qualitative support for the NADPH pool.
- G6PD has known clinical safety sensitivity, so Phase 1A content must stay educational and uncertainty-labeled.
- The current model does not infer hemolysis risk, medication safety, or patient-specific clinical advice.